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Maria Lauda Tomasi Selected Research

Methionine Adenosyltransferase

1/2021Deregulated 14-3-3ζ and methionine adenosyltransferase α1 interplay promotes liver cancer tumorigenesis in mice and humans.
10/2017S-adenosylmethionine and methylthioadenosine inhibit cancer metastasis by targeting microRNA 34a/b-methionine adenosyltransferase 2A/2B axis.
11/2015Methionine adenosyltransferase α2 sumoylation positively regulate Bcl-2 expression in human colon and liver cancer cells.
7/2013Polyamine and methionine adenosyltransferase 2A crosstalk in human colon and liver cancer.
12/2010Liver-specific deletion of prohibitin 1 results in spontaneous liver injury, fibrosis, and hepatocellular carcinoma in mice.

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Maria Lauda Tomasi Research Topics

Disease

6Neoplasms (Cancer)
01/2021 - 09/2012
5Hepatocellular Carcinoma (Hepatoma)
01/2021 - 06/2010
4Liver Neoplasms (Liver Cancer)
01/2021 - 09/2012
3Carcinogenesis
01/2021 - 06/2013
2Breast Neoplasms (Breast Cancer)
01/2019 - 09/2012
2Colorectal Neoplasms (Colorectal Cancer)
10/2017 - 06/2013
2Colonic Neoplasms (Colon Cancer)
07/2013 - 09/2012
2Fibrosis (Cirrhosis)
10/2012 - 12/2010
1Cholangiocarcinoma
01/2021
1Mitochondrial Diseases (Mitochondrial Disease)
12/2019
1Hypoxia (Hypoxemia)
01/2018
1B-Cell Lymphoma (Lymphoma, B Cell)
01/2018
1Alcoholic Liver Diseases (Alcoholic Liver Disease)
01/2018
1Neoplasm Metastasis (Metastasis)
10/2017
1Inflammation (Inflammations)
01/2016
1Sarcoma (Soft Tissue Sarcoma)
05/2015
1Adenocarcinoma
07/2013
1Paranoid Disorders (Paranoia)
07/2013
1Gastrointestinal Neoplasms (Gastrointestinal Cancer)
06/2013
1Genomic Instability
03/2009

Drug/Important Bio-Agent (IBA)

5Methionine AdenosyltransferaseIBA
01/2021 - 12/2010
3Mitogen-Activated Protein KinasesIBA
01/2019 - 06/2010
3Proteins (Proteins, Gene)FDA Link
06/2013 - 03/2009
2Ethanol (Ethyl Alcohol)IBA
12/2019 - 01/2019
2Methionine (L-Methionine)FDA Link
01/2018 - 09/2012
2Pemetrexed (MTA)FDA Link
10/2017 - 09/2012
2Mitogen-Activated Protein Kinase Kinases (MEKs)IBA
05/2015 - 06/2013
2Messenger RNA (mRNA)IBA
09/2012 - 03/2009
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
12/2019
1lipid transfer protein (glycolipid transfer protein)IBA
01/2019
1CalciumIBA
01/2019
1Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA
01/2019
1EnzymesIBA
01/2018
1Glucose (Dextrose)FDA LinkGeneric
01/2018
1NF-kappa B (NF-kB)IBA
01/2018
1CateninsIBA
01/2018
1Cytochrome P-450 CYP2E1 (CYP2E1)IBA
01/2018
1MicroRNAs (MicroRNA)IBA
10/2017
1S-Adenosylmethionine (Ademetionine)IBA
10/2017
1Interleukin-6 (Interleukin 6)IBA
10/2017
1LipopolysaccharidesIBA
01/2016
1EndotoxinsIBA
01/2016
1PutrescineIBA
07/2013
1PolyaminesIBA
07/2013
1Small Interfering RNA (siRNA)IBA
07/2013
1MitogensIBA
07/2013
1Ornithine Decarboxylase (Decarboxylase, Ornithine)IBA
07/2013
1Pharmaceutical PreparationsIBA
07/2013
1Jagged-1 ProteinIBA
06/2013
1LigandsIBA
06/2013
15'-methylthioadenosineIBA
09/2012
1Ubiquitin-Conjugating EnzymesIBA
09/2012
1ProhibitinsIBA
12/2010

Therapy/Procedure

1Therapeutics
06/2013
1Ligation
10/2012